Effect of Quercetin on Asthma and Nasal Allergies as an Immunomodulator: Review

Abstract

Quercetin is a flavonoid found in nature, and is rich in antioxidants. It is recognized as an
important natural substance, notable for its potent effects in modulating the immune system
and its anti-inflammatory characteristics. Many fruits and vegetables, such as onions,
shallots, apples, and different berries, contain quercetin. Consequently, this review aims to
elucidate the function of quercetin as an immune enhancer and its significance in managing
asthma and nasal allergies. A variety of research studies involving both human and animal
subjects have been conducted, with ongoing investigations both in vitro and in vivo
continuing until 2024. The effects of quercetin as an anti-inflammatory agent and antiasthmatic conditions, it is also linked to decreased levels of interleukin IL-4, inhibition of
histamine release, and a decrease in the synthesis of pro-inflammatory cytokines and
leukotrienes. Quercetin has the potential to diminish the creation of antigen-specific IgE
immunoglobulin and enhance the balance between Th1 and the responses. inconclusion: the
characteristics of quercetin could serve as a therapeutic approach for conditions such as
asthma and nasal allergies.